Figure 2.

Schematic of representation of the SfABCC2 gene. The two-marker system (SNP and +GC) used to diagnose the three segregating haplotypes is presented on the structure of the SfABCC2 gene, along with the rubric used to identify each haplotype. This schematic applies to Family 1, however in Family 26 the S allele behaved dominantly, rather than codominantly, in R₂S backgrounds, making it impossible to separate SS from R₂S genotypes. The intron/exon structure of SfABCC2 is given, and the protein domains are color-coded and shown below their corresponding exons. The location of the R₂ insert and splice disruption sites on exon 4 is also marked. Finally, three numbered magenta triangles mark the location of the putatively paralogous peptides detected in in the resistant individuals using LC-MS/MS. Their numbering is as follows 1) FFDTNPSGR, 2) SSLISALFR, and 3) SKISIIPQEPVLFSASLR.