Table 3.

Predictive factors for the development of HCC.

	Unadjusted HR (95% CI)	P value	Adjusted HR (95% CI)	P value
Age (5-Year intervals)	1.19 (1.12–1.27)	<0.001	1.29 (1.18–1.40)	<0.001
Male sex	1.62 (1.23–2.15)	0.001	1.64 (1.15–2.34)	0.006
Ethnicity
Non-Hispanic < 2 MRF	Referent	Referent	Referent	Referent
Hispanic < 2 MRF	1.14 (0.73–1.79)	0.570	1.42 (0.80–2.54)	0.230
Non-Hispanic ≥ 2 MRF	1.35 (0.99–1.82)	0.052	1.00 (0.68–1.48)	0.990
Hispanic ≥ 2 MRF	2.17 (1.50–3.13)	<0.001	1.89 (1.20–2.97)	0.006
CTP score (continuous)	1.16 (1.08–1.25)	<0.001	1.14 (1.06–1.24)	0.001
SVR status
SVR	Referent	Referent	Referent	Referent
No SVR	2.88 (1.48–5.60)	0.002	2.53 (1.18–5.42)	0.017

Multiplicative interaction P-value: 0.44.

Abbreviations: CTP, Child- Turcotte-Pugh; HCC, hepatocellular carcinoma; MRF, metabolic risk factor; SVR, sustained virologic response.