Fig. 3.
Silencing of forebrain pyramidal neurons did not affect spatial learning during massed training. A) Escape latencies during training did not differ between CON and ATD animals (CON, n = 40; ATD, n = 14). B) Number of platform crossings during the IMM probe did not differ between CON and ATD animals; C) Plot of quadrant dwell times during the IMM probe shows that neither CON nor ATD animals spent more time in any given quadrant. G = goal, O = opposite, A = adjacent. D) Plot of quadrant biases (percentage of animals spending most of their time in a given quadrant) during the IMM probe shows that neither CON nor ATD animals exhibited a quadrant bias. E) DtP measured across 10 or 30 s of the IMM probe did not differ between CON and ATD animals. The black circle on the Y-axis indicates the platform edge. The open circle marks starting location for all animals (710 mm).