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. 2018 May 8;8:7297. doi: 10.1038/s41598-018-25453-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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CM from microglia delays Aβ42-induced neuronal death. MTT assay on SH-SY5Y treated with Aβ42 alone or in combination with BDNF (1 ng/ml) or GNF (100 nM) in non-conditioned medium (A) and in CM from untreated (CMC), Aβ-treated (5 + 18 h; CMA), BDNF-treated (CMB) or Aβ + GNF-treated (CMAG) pMG (B). Values are mean ± SEM with n = 5. *p < 0.05 vs. respective controls. **p < 0.05 vs CMA + Aβ. Data were analyzed by one-way ANOVA followed by Newman-Keuls test for significance.