Fig. 5.

Membrane activity and antimicrobial action study of nested hexagons. a Proposed model of transmembrane channels formed by G3. b Current traces (15 s) of G2 (5.0 nM), G3 (5.0 nM), and G4 (40 nM) in the planar lipid bilayer at +100 mV in KCl (1.0 M) solution. c 3D deconvolution fluorescence microscopy images of bacteria cells with and without treatment of nested hexagons (4 μM, FM4-64 dye was added) Scale bar: 1 μm. TEM images of MRSA cells (d), MRSA cells without treatment. e−g MRSA cells treated by G2: e supramolecules aggregated on the cell surface; f, g cells were damaged and cell death was observed. Scale bars: 500 nm. Ultrathin sectioning TEM images of MRSA after treatment with h, i G2 (25 nM); j, k G3 (25 nM). MRSA cells had well-defined cell wall (CW) but disrupted cell membranes (CM). Scale bars: 200 nm