Table 4.
Comparison of the antimicrobial susceptibilities of biofilm-forming and non-biofilm-forming Acinetobacter baumannii isolates.
| Antimicrobial agent | Biofilm-forming isolates (n = 71) | Non-biofilm-forming isolates (n = 202) | p value b | ||
|---|---|---|---|---|---|
| Resistance, no. (%) | MIC90 (µg/mL) | Resistance, no. (%) | MIC90 (µg/mL) |
||
| Amikacin | 44 (62.0) | >2048 | 151 (74.8) | >2048 | 0.040 |
| Gentamicin | 57 (80.0) | >2048 | 181 (89.6) | >2048 | 0.043 |
| Ceftazidime | 56 (78.9) | 512 | 186 (92.1) | 1024 | 0.003 |
| Cefepime or cefpirome | 48 (67.6) | 128 | 157 (77.7) | 256 | 0.009 |
| Piperacillin/tazobactam | 52 (73.2) | 4096/4 | 163 (80.7) | >4096/4 | 0.187 |
| Ampicillin/sulbactam | 46 (64.8) | 64/32 | 141 (69.8) | 128/64 | 0.434 |
| Ciprofloxacin | 55 (77.5) | 256 | 187 (92.6) | 512 | 0.001 |
| Imipenem | 39 (54.9) | 64 | 139 (78.1) | 64 | 0.035 |
| Meropenem | 39 (54.9) | 64 | 142 (78.5) | 128 | 0.018 |
| Tigecycline | 19 (26.8) | 4 | 39 (19.3) | 4 | 0.187 |
| Colistin | 0 | 2 | 0 | 2 | — |
| Multidrug resistancea | 58 (81.7) | — | 188 (93.1) | — | 0.006 |
aDefinition: resistance to three or more of the following classes of antimicrobial agents: anti-pseudomonal cephalosporins, anti-pseudomonal carbapenems, ampicillin/sulbactam, fluoroquinolones and aminoglycosides.
bp value: The difference in resistance rate to antibiotics between biofilm-forming isolates and non-biofilm-forming isolates.