Table 1.
Baseline characteristics of patients in each group
| Characteristics | Extubation success | Extubation failure | p value |
|---|---|---|---|
| Number of patients, n | 311 | 24 | |
| Male sex, n (%) | 193 (62.1) | 17 (70.8) | 0.512 |
| Age, median (IQR) | 71 (62–79) | 72 (64–78) | 0.581 |
| BMI, median (IQR) | 22.7 (20.3–25.2) | 21.05 (17.3–24.8) | 0.115 |
| GCS, median (IQR) | 11 (10–11) | 11 (10–11) | 0.667 |
| CAM-ICU, positive (%) | 40 (12.9) | 8 (33.3) | 0.012 |
| APACHE II score, median (IQR) | 20 (17–24) | 24 (22–28) | < 0.001 |
| SAPS II score, median (IQR) | 41 (32–51) | 51 (46–59) | < 0.001 |
| In–out balance, median ml (IQR) | 2959 (1000–5322) | 2676 (793–4500) | 0.701 |
| Intubation days, median (IQR) | 2 (1–3) | 4 (2–6) | 0.001 |
| P/F ratio, median (IQR) | 300 (250–367) | 275 (218–326) | 0.036 |
| TV, median L (IQR) | 0.44 (0.36–0.55) | 0.47 (0.40–0.66) | 0.139 |
| MV, median L (IQR) | 6.90 (5.60–8.19) | 7.90 (5.76–9.75) | 0.087 |
| RSBI, median breaths/min/L (IQR) | 37.2 (26.4-48.9) | 38.2(16.9-51.3) | 0.691 |
| Length of ICU stay, median (IQR) | 4 (2–6) | 12 (6–16) | < 0.001 |
| Length of hospital stay, median (IQR) | 20 (14–36) | 48 (27–55) | < 0.001 |
| 28-Day mortality, n (%) | 3 (1.0) | 3 (12.5) | 0.006 |
| In-hospital mortality, n (%) | 10 (3.2) | 5 (20.8) | 0.002 |
| Baseline IAP, mm H20, median (IQR) | 7.9 (4.0–10.0) | 8.0 (5.7–13.0) | 0.19 |
| ΔIAP, mm H2O, median (IQR) | 39.0 (24.0–57.0) | 25.5 (19.8–38.3) | 0.012 |