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. 2016 Apr 1;2(2):69–73. doi: 10.1016/j.aninu.2016.03.007

Table 1.

Part of the amino acid transport system in mammalian intestinal epithelial cells.

System cDNA Gene AA substrate Mechanism Iron Expression
ASC ASCT2 SLC1A5 A,S,C,T,Q A Na+ AM
B0 B0AT1 SLC6A19 AA0 S Na+ AM
B0,+ ATB0,+ SLC6A14 AA0, AA+, β-Ala S Na+, Cl AM
b0,+ rBAT/b0,+AT SLC3A1/SLC7A9 R,K,O A AM
IMINO IMINO SLC6A20 P,HO-P S Na+, Cl AM
L 4F2hc/LAT2 SLC3A2/SLC7A8 AA0 except P A BM
PAT PAT1 SLC36A1 P,G,A,β-Ala S H+ BM
T TAT1 SLC16A10 F,Y,W U BM
XAG EAAT3 SLC1A1 E,D S Na+, H+, K+ AM
y+L 4F2hc/y+LAT1 SLC3A2/SLC7A7 K,R,Q,H,M,L A Na+ BM
y+L 4F2hc/y+LAT2 SLC3A2/SLC7A6 K,R,Q,H,M,L,A,C A Na+ BM
A SNAT2 SLC38A2 G,P,A,S,C,Q,N,H S Na+ AM, BM
Xc 4F2 hc/xCT SLC3A2/SLC7A11 E A AM, BM
y+ CAT-1 SLC7A1 R, K、O, H U AM, BM

A = anti-port; AM = apical membrane; AA0 = neutral amino acids; S = symport; AA+ = cationic amino acids; BM = basolateral membrane; U = uni-port.