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Model of the gating mechanism mediated by the prokaryotic channel from Gloeobacter violaceus GLIC. Left, the pH7 closed state; right, the pH4 open state. (a) View from the top illustrating the twisting and blooming motion, indicated by black arrows. (b) View from the side schematically illustrating the transmission of the signal through the ECD–TM interface. Reproduced from Sauguet et al. [86, fig. 4].
