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Antiseizure activity of GX in fully kindled WT and δΚΟ mice. (A) GX dose-dependent curves of behavioral seizure activity and (B) afterdischarge (AD) duration. (C) Time courses for behavioral seizure stage and (D) AD duration with GX at 10 mg/kg s.c. in fully kindled mice. (E) GX dose-dependent responses of behavioral seizure activity and (F) AD duration in WT and δΚΟ mice. Each point or bar represents mean ± S.E.M. *P < 0.05 vs. WT (n = 6–9 animals per group).
