Figure 7.
Pulmonary and systemic arterial pressures after LD67 inhalation exposure in invasively catheterized rats with oxygen administration (0.8 FiO2, squares with dashed line) compared with untreated controls (triangles with solid line). (A) The mean pulmonary artery pressure (MPAP) was obtained hourly after chlorine inhalation exposure with and without oxygen administration. Note the abrupt increase in MPAP early after chlorine inhalation, with oxygen therapy tending to normalize MPAP after administration (not significant). (B) Mean systemic artery pressure (MAP) obtained hourly after chlorine inhalation exposure with and without oxygen. No significant change occurred in MAP after chlorine inhalation or with oxygen. Values represent means ± SEM; statistical analysis via unpaired t test; *P < 0.05. n = 14 in control group, n = 5 in oxygen-treated group.