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. 2018 May 8;18:147. doi: 10.1186/s12906-018-2217-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Effect of LAC117 on the proliferation and apoptosis in HepG2 xenografts. a Tumors were immunostained for PCNA, cleaved caspase-3, p-AKT, and p-mTOR including H&E staining. b Scheme for how LAC117 induces apoptosis and inhibits the growth of HCC cells. The results were observed by microscopy at × 400 magnification