Table 3.
Significant differentially expressed miRNAs between VN and VA treated groups and their predicted targets
| miRNA | Log2 fold change (VA/VN): miRNA transcriptome | Log2 fold change (VA/VN): qPCR | Targets | Log2 fold change (VA/VN): target genes | Annotation |
|---|---|---|---|---|---|
| bbe-miR-210-5p | −2.870407322 | −1.517940555 | Unigene5114_All | 1.060349045 | p63-like transcription factor |
| CL3703.Contig2_All | 1.088996766 | interferon alpha-inducible protein 6 isoform 1 | |||
| Unigene10324_All | 1.201529506 | Mucin-5 AC | |||
| Unigene444_All | 1.267391152 | Mucin-2 | |||
| Unigene7288_All | 2.244651906 | Kazal-type serine proteinase inhibitor 4 | |||
| age-miR-127 | −2.588007591 | −1.649872672 | CL878.Contig1_All | 1.4821571 | lectin 3 |
| CL793.Contig1_All | 1.830735508 | C-type lectin | |||
| Unigene711_All | 1.769299871 | minicollagen 1 | |||
| hsa-miR-211-5p | −5.092799743 | −1.708656758 | CL1084.Contig1_All | 1.166678298 | Cytochrome P450 2 L1 |
| Unigene23044_All | 1.357617048 | Mucin-19 | |||
| Unigene444_All | 1.267391152 | Mucin-2 | |||
| Unigene20688_All | 1.711317404 | nuclear transcription factor Tfp1 | |||
| CL1920.Contig3_All | 1.465320468 | innexin 3 | |||
| tch-miR-210 | −2.815959538 | −1.589144004 | Unigene5114_All | 1.060349045 | p63-like transcription factor |
| CL3703.Contig2_All | 1.088996766 | interferon alpha-inducible protein 6 isoform 1 | |||
| Unigene10324_All | 1.201529506 | Mucin-5 AC | |||
| Unigene444_All | 1.267391152 | Mucin-2 | |||
| Unigene7288_All | 2.244651906 | Kazal-type serine proteinase inhibitor 4 | |||
| bmo-miR-278-5p | −5.70048232 | −1.446914278 | Unigene10827_All | 1.273096701 | cytochrome P450 49a1 |
| Unigene6914_All | 1.242144205 | Mucin-5B | |||
| bta-miR-22-5p | −4.70048232 | −1.998632464 | Unigene1405_All | 1.881244868 | Caspase-2 |
| Unigene1487_All | 5.962236179 | Peritrophin-1 | |||
| Unigene10827_All | 1.273096701 | cytochrome P450 49a1 | |||
| Unigene7890_All | 1.269494038 | cathepsin C | |||
| bmo-miR-9c-5p | −4.802020347 | −1.286244383 | Unigene20818_All | 1.499249658 | Caspase Nc |
| Unigene5907_All | 12.02859678 | Heat shock-related 70 kDa protein 2 | |||
| Unigene24983_All | 5.12621573 | High mobility group protein B3 | |||
| CL183.Contig3_All | 1.643990119 | Caspase-3 | |||
| Unigene21910_All | 1.036005418 | Cytochrome P450 3A2 | |||
| dpu-miR-193 | −1.274473703 | −1.428703251 | Unigene18431_All | 2.401408994 | Chymotrypsin BII |
| dre-miR-107b | 3.106872602 | 1.737363291 | CL1260.Contig2_All | −1.153013031 | Tumor protein p53-inducible protein 11 |
| mja-miR-6489-5p | 1.182514886 | 5.323473519 | CL1919.Contig1_All | −1.964210604 | sarcoplasmic calcium-binding protein |
| Unigene15684_All | −1.244264787 | suppressors of cytokine signaling-5 | |||
| bta-miR-4286 | 4.943373869 | 1.464858155 | CL1919.Contig1_All | −1.964210604 | sarcoplasmic calcium-binding protein |
| sha-miR-10b | −1.161907157 | −1.211066559 | Unigene2751_All | 1.405570272 | Substance-K receptor |
| Unigene22975_All | 1.035210199 | Cytokine receptor | |||
| Unigene15784_All | 1.371799521 | Latrophilin-3 |