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. 2018 May 8;16:118. doi: 10.1186/s12967-018-1495-6

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© The Author(s) 2018, corrected publication July 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Heatmap showing the most variable 2000 genes in the RNA-Seq data. Sample and gene clustering was applied. The color indicates the log2-foldchange in comparison to the overall samples mean of the corresponding gene