Fig. 3.

Efficacy of SJS in PR8 infected mouse model. Mice was administrated orally with 200 μl of 1 g/kg/day SJS, 90 mg/kg/d oseltamivir or water for 7 days. Conditions of mice were monitored for consecutive 14 days. a SJS protected the mice infected with 3 LD₅₀ of PR8 virus. b Body weight changes of mice were monitored daily. Oseltamivir and SJS reduced c lung index and d lung viral load of PR8 infected mice compared with untreated mice. Three mice from each group were randomly selected and sacrificed on the fourth day and their lungs were extracted. The lung viral load was determined by plaque assay