Table 4.
Association of serum 25(OH) D concentrations and outcomes in HIV-infected TB suspects
| Variable | Serum 25(OH) D ng/ml Median(IQR) | p-value | Univariate Odds ratio (95%CI) |
Multivariate Odds ratiob (95%CI) |
|---|---|---|---|---|
| PTB status n = 284 | 1.84 (1.1–3.2) | |||
| 1. PTB+ n = 145 | 25.3 (18.0–33.7) | 0.0003 | 1.91 (1.1–3.2) | |
| 2. PTB− n = 139 | 20.4 (14.6–26.9) | Referent | ||
| 8-week outcome n = 265a | 0.90 (0.5–1.7) | |||
| 1. Alive n = 190 | 21.91 (16.9–31.1) | 0.767 | Referent | |
| 2. Deceased n = 75 | 21.97 (15.8–31.7) | 0.93 (0.5–1.7) | ||
| Cause of Death n = 75 | 4.25 (1.1–16.2) | |||
| 1. PTB n = 49 | 23.28 (16.6–34.8) | 0.059 | 3.19(0.9–10.7) | |
| 2. Other | 18.47 (15.0–29.4) | Referent | ||
| Hospital Stay n = 245a | 0.87 (0.5–1.6) | |||
| 1. ≤7 days n = 179 | 22.14 (17.0–30.7) | 0.740 | Referent | |
| 2. > 7 days | 22.10 (14.5–35.7) | 0.89 (0.5–1.7) | ||
Key: IQR interquartile range, CI confidence interval, PTB pulmonary tuberculosis, TB tuberculosis. p-values of ≤ 0.05 were considered statistically significant. asome lost to follow up or incomplete data in records and bOR adjusted for binaries of gender, age (≥50 or < 50 years), CD4 cell count (≥200 or < 200 cells/μL) and cART status (experienced or naïve)