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. 2018 May 8;9:18. doi: 10.1186/s13293-018-0177-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Differential lung miRNA expression in females exposed to O₃ vs. FA at different stages of the estrous cycle. Cluster analysis of 84 miRNAs measured in lung extracts from female mice exposed to 2 ppm of O₃ or FA for 3 h. Animals were exposed to O₃ or FA at different stages of the estrous cycle (D1 = diestrus 1/metestrus, D2 = diestrus 2, P = proestrus, E = estrus). Estrous cycle stage was confirmed by vaginal smear and circulating sex hormone levels. FA filtered air, O3 ozone. Number of mice per group FA_D1 (n = 4), FA_D2 (n = 4), FA_P (n = 9), FA_E (n = 6), O3_D1 (n = 3), O3_D2 (n = 3), O3_P (n = 9), O3_E (n = 4)