Fig. 1.

Interaction between neighborhood poverty and maternal diet quality during pregnancy (DQI-P). a Displays the regression coefficients stratified by different quintiles of diet quality index (DQI-P). Regression coefficients are interpreted as the adjusted difference in LINE-1%-methylation between a quartile of neighborhood poverty and the lowest neighborhood poverty quartile (reference). Each different color corresponds to a different stratum of DQI-P as indicated by the legend (e.g., purple is the first quintile of DQI-P and orange is the fifth quintile of DQI-P). b Displays the slopes for neighborhood poverty (x axis) on LINE-1%-methylation (y axis) at different levels of DQI-P (e.g., dark blue line is the slope for observations at + 1 standard deviation for DQI-P and the light gray line is the slope for observations at − 1 standard deviation for DQI-P). c Displays the simple slopes for neighborhood poverty (y axis) across different levels of DQI-P (x axis). The pink portion of the confidence interval indicates no statistical significance (p > 0.05) between poverty and LINE-1 methylation and the blue-green portion of the confidence interval indicates statistical significance (p < 0.05) between poverty and LINE-1 methylation. The vertical dotted line indicates the point at which the relationship between poverty and LINE-1 methylation becomes statistically significant