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. 2018 May 8;13:87. doi: 10.1186/s13014-018-1041-y

Table 3.

Number of Fractions and Doses

Number of fractions of the first treatment (SBRT) Number Percent
Single Fraction
30 Gy/ 1 fr 11 42
23 Gy/1 fr 3 11
Multiple Fractions
45 Gy/ 3fr 3 11
50 Gy/5 fr 3 11
60 Gy/ 30 fr a 5 18
30 Gy/ 10 fr b 2 7
Number of fractions of the re-irradiation (SBRT)
Single Fraction
30 Gy/ 1 fr 4 15
23 Gy/1 fr 3 11
Multiple Fractions
54 Gy/ 3 fr 3 11
45 Gy / 3fr 5 18
50 Gy/ 5fr 8 30
30Gy/fr 5 4 15
Medium biological effective dose (10Gy) (BED10) Dose Range
I Treatment 97,2 Gy 40–120
Re-Irradiation 100,6 Gy 48–151,2
Medium equivalent dose in 2 Gy (10 Gy) (EQD2) DOSES RANGE
I treatment 81 Gy 32,5–100 Gy
Re-Irradiation 93,8 Gy 40–126 Gy
Cumulative medium BED (10) 197,8 Gy 88–271,2 Gy
Cumulative medium EQD2 (10) 164,8 Gy 72,5–226 Gy
Median biological effective dose (10Gy) (BED10) Doses Range
I Treatment 112,5 Gy 40–120 Gy
Re-Irradiation 100 Gy 48–151,2 Gy
Median equivalent dose in 2 Gy (10 Gy) (EQD2) Doses Range
I treatment 93,8 Gy 32,5–100 Gy
Re-Irradiation 83,3 Gy 40–126 Gy
Cumulative median bed (10) 200 Gy 88–271,2 Gy
Cumulative median EQD2 (10) 166,7 Gy 72,5.226 Gy

aTreatment done by IMRT technique

b Treatment done by 3D technique