Table 4.

Comparison of GWAS findings for DME and PDR with a previously published GWAS for sight-threatening DR in a Caucasian population (Grassi et al., 2011 [14])

p < 0.006 was required for significance to account for the eight loci tested (as separated by horizontal bold lines). Nominally significant p-values (p < 0.05) are shown in bold. Proxy SNPs were used in this study when published SNPs were not available. Proxy SNPs were selected based on r² value with the reported SNP in the CEU population of HapMap. 95% CI for the OR was not reported by Grassi et al., 2011 [14])

^aIn Grassi et al. 2011, the MALRD1 locus was labelled as C10orf112 and NPIPB8 was labelled as CCDC101^b and SULT1A^c

^dSNP with lowest p-value within 50 kb of the published SNP (no appropriate proxy SNP identified)