Table 2. . Mutagenic properties of compound 1 determined by Ames test.
Test compound | Number of His+ revertants/plate | ||
---|---|---|---|
Concentration (μg/plate) | Salmonella typhi TA 1535 | Salmonella typhi TA 1538 | |
DMSO | 5.0 | 22 | 31 |
Compound 1 | 2.5 | 4 | 10 |
5.0 | 8 | 18 | |
7.5 | 22 | 25 | |
10.0 | 34 | 61 | |
4NOP | 5.0 | 735 | 835 |
4NOP: 4-Nitro-o-phenylenediamine.