Table 2. . Mutagenic properties of compound 1 determined by Ames test.
| Test compound | Number of His+ revertants/plate | ||
|---|---|---|---|
| Concentration (μg/plate) | Salmonella typhi TA 1535 | Salmonella typhi TA 1538 | |
| DMSO | 5.0 | 22 | 31 |
| Compound 1 | 2.5 | 4 | 10 |
| 5.0 | 8 | 18 | |
| 7.5 | 22 | 25 | |
| 10.0 | 34 | 61 | |
| 4NOP | 5.0 | 735 | 835 |
4NOP: 4-Nitro-o-phenylenediamine.