Table 1.
Patients’ characteristics
| Characteristic | Number of patients (%) | |
|---|---|---|
| Age (years) | Median: 68 (range, 51–80) | |
| Sex | Male | 56 (60.2) |
| Female | 37 (39.8) | |
| Location | Perihilar bile duct | 25 (26.9) |
| Distal bile duct | 52 (55.9) | |
| Ampulla of Vater | 16 (17.2) | |
| Tumor satellites | Present | 2 (2.2) |
| Absent | 91 (97.8) | |
| Pathologic T stage | T1–2 | 55 (59.1) |
| T3–4 | 38 (40.9) | |
| No. of LN dissection | ≤8 | 50 (53.8) |
| > 8 | 43 (46.2) | |
| Pathologic N stage | N0 | 63 (67.7) |
| N+ | 30 (32.3) | |
| Histology | Adenocarcinoma | 91 (97.8) |
| Others | 2 (2.2) | |
| Histologic differentiation | WD-MD | 74 (79.6) |
| PD | 19 (20.4) | |
| Lymphovascular invasion | Yes | 32 (34.4) |
| No | 61 (65.6) | |
| Perineural invasion | Yes | 46 (49.5) |
| No | 47 (50.5) | |
| Resection margin status | R0 | 59 (63.4) |
| Close RM-R1 | 34 (36.6) | |
| Adjuvant chemotherapy | Fluoropyrimidine based | 8 (8.6) |
| Gemcitabine based | 9 (9.7) | |
| No | 76 (81.7) |
LN lymph node, N0 negative lymph node, N+ positive lymph node, WD well differentiation, MD moderate differentiation, PD poor differentiation, RM resection margin