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. 2018 May 9;22:12. doi: 10.1186/s40824-018-0121-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Preparation of collagen spheroids. a Collagen spheroids containing hPMSCs and hFDM-hep; b–d Collagen spheroids containing hPMSCs, hFDM-hep and live cell tracking dye (PKH26) at different time points in vitro; e Release profile of TGF-β1 from three different groups of collagen spheroids for 28 days in vitro. CS: collagen spheroid. Scale bar is 200 μm