Table 3.
Hormone profile of CD1 mice supplemented with sweeteners for 12 weeks.
| Baseline (3rd week) | Middle (9th week) | Final (15th week) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| CL | SUC | SUCL | ST | CL | SUC | SUCL | ST | ||
| Mean ± SD (n = 8) | Median ± SD (n = 8) | Median ± SD (n = 8) |
Median ± SD (n = 8) | Median ± SD (n = 8) | Median ± SD (n = 8) |
Median ± SD (n = 8) | Median ± SD (n = 8) | Median ± SD (n = 8) | |
| GIP | 123.2 | 37.14 | 66.57 | 75.59 | 86.59 | 127 | 121 | 93 | 145 |
| Insulin | 545.9 | 260 | 196 | 602 | 1282a | 938 | 1143 | 939 | 1360a |
| Leptin | 275.5 | 245 | 181 | 187 | 456 | 380 | 459 | 446 | 421 |
| HOMA Index | 181.4 | 340 | 132 | 240 | 451a | 456 | 390 | 396 | 489a |
The values represent the median in pg/mL for each determination; a nonparametric Kruskal-Wallis testa was made of independent samples to compare the differences between the subgroups: the differences were considered significant with a p value < 0.05∗. CL = Control, SUC = Sucrose, SUCL = Sucralose, and ST = Stevia.