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. 2018 May 2;2(9):1000–1012. doi: 10.1182/bloodadvances.2017013953

Table 1.

The clinical characteristics of the AA patients possessing HLA-A allele–lacking leukocytes

Cases PB count % of GPI-AP granulocytes
Case no. Age/sex Original diagnosis Disease duration, y Treatment Response to treatment Leukocyte/ANC, ×109/L Hemoglobin, g/dL Platelet, ×109/L Reticulocyte, ×106/L At diagnosis At sampling
1 84/F SAA 8 ATG + CsA CR 4.03/2.22 11.1 16.8 60 0.050 NE
2 79/F NSAA 12 CsA CR 3.62/2.36 12.3 133 63 0.022 0.001
3 38/F NSAA 14 CsA CR 5.47/4.44 11.9 136 75 1.050 0.001
4 92/F SAA 17 CsA CR 3.43/1.67 11.8 98 38 0.005 NE
5 44/M SAA 11 AS CR 3.92/2.88 13.7 182 37 0 NE
6 66/F SAA 16 ATG + CsA CR 5.78/3.29 10.9 196 49 0.367 NE
7 39/F VSAA 15 ATG + CsA CR 4.57/2.58 14.3 173 68 0 NE
8 74/F NSAA 25 CsA CR 4.21/2.31 13.9 167 NE 0 NE
9 27/M NSAA 14 ATG + CsA CR 2.44/1.30 14.8 132 68 1.140 0.052
10 42/M SAA 10 CsA CR 3.00/1.74 14.3 159 63 0.180 NE
11 54/M NSAA 2 CsA + AS CR 3.21/1.54 12.3 109 75 3.500 NE
12 53/F VSAA 3 Romiplostim CR 6.30/3.81 14.2 147 47 0 NE
13 50/M NSAA 30 CsA + AS CR 4.32/2.57 14.4 78 35 0 NE
14 58/M SAA 11 ATG + CsA CR 3.76/1.77 14.4 208 59 0 NE
15 55/F PNH 13 CsA CR 3.54/2.29 14 111 79 39.16 0.001
→NSAA

ANC, absolute neutrophil count; AS, anabolic steroids; ATG, antithymocyte globulin; CR, complete response; CsA, cyclosporine; F, female; GPI-AP, glycosylphosphatidylinositol-anchored membrane proteins deficient; M, male; NE, not evaluated; NSAA, nonsevere aplastic anemia; PB, peripheral blood; PNH, paroxysmal nocturnal hemoglobinuria; SAA, severe aplastic anemia; VSAA, very severe aplastic anemia.