Table S2.

Multivariate analysis of the patients with hilar carcinoma (N = 75)

Variable	Multivariate analysis
	HR	95% CI	P-value
Age ≥65 years vs <65 years	0.697	0.268–1.815	0.460
Female vs male	1.528	0.591–3.948	0.382
Depth of tumor invasion
T2 vs T1	4.281	0.331–55.335	0.265
T3 vs T1	2.712	0.147–50.016	0.502
T4 vs T1	11.119	0.396–311.937	0.157
Lymph node status (positive vs negative)	0.618	0.140–2.731	0.525
Metastasis (positive vs negative)	0.140	0.015–1.289	0.083
Histologic differentiation
Poorly vs well and moderately differentiated	1.132	0.397–3.231	0.817
Lymphovascular invasion (positive vs negative)	1.493	0.348–6.409	0.590
Perineural invasion (positive vs negative)	0.300	0.115–0.782	0.014
Resection margin (positive vs negative)	1.676	0.662–4.239	0.276
Hemoglobin (<110 g/L vs ≥110 g/L)	1.373	0.262–7.196	0.708
CEA (≥4.7 ng/mL vs <4.7 ng/mL)	1.889	0.697–5.119	0.211
CA19-9 (≥39 U/mL vs <39 U/mL)	2.370	0.570–9.853	0.235
LDH (≥271 U/L vs <271 U/L)	2.200	0.561–8.627	0.258

Note: Data in bold indicates P < 0.05.

Abbreviations: CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; LDH, lactic dehydrogenase.