TABLE 3.

Efficacy and Safety of Catheter Ablation of AF in the Very Elderly

First Author (Ref. #)	AF Type	Age (yrs)	Mean Follow-Up Duration	Success Rate	Complication Rate	Ablation of Nonpulmonary Vein Triggers
Santangeli et al. (76)	Paroxysmal and persistent	≥80, <80	18 months	69% vs. 71% after first ablation 87% vs. 85% after second ablation	4% vs. 4.9%	84% vs. 69%, driven by difference in paroxysmal AF
Bunch et al. (78)	Paroxysmal and persistent	≥80 (n = 35), <80 (n = 717)	12 months	78% vs. 75%	7.5 vs. 4.1% (p = NS)	80% vs. 78% had additional linear ablation
Tan et al. (77)	Paroxysmal, persistent, and long-standing persistent	≥80, 70–79, 60–69	18 months	70% vs. 72% vs. 74%*	Total complication rate 2%	Not reported
Zado et al. (75)	Paroxysmal and persistent	>75 (n = 34), 65–75 (n = 185), <65 (n = 948)	27 months	86% vs. 84% vs. 89%	2.9% vs. 1.7% vs. 1.6%	13% vs. 17% vs. 12%

^*More patients ≥80 years of age were maintained on antiarrhythmic drugs (26% vs. 20% vs. 16%; p < 0.05 and p < 1.01, respectively).

AF = atrial fibrillation; NS = nonsignificant.