Table 2.
Experimental design detailing quantity of FSH and LH in superstimulatory preparation1
| Day/time | Low LH: Flex H only | High LH: Flex H + Pluset | ||||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||
| FSH (IU) | LH (IU) | Flex H (mL) | Pluset (mL) | FSH (IU) | LH (IU) | Flex H (mL) | Pluset (mL) | |
| Day 9, p.m. | 158 | 53 | 3.00 | — | 158 | 53 | 3.00 | — |
| Day 10, a.m. | 144 | 48 | 2.75 | — | 144 | 48 | 2.75 | — |
| Day 10, p.m. | 118 | 39 | 2.25 | — | 118 | 39 | 2.25 | — |
| Day 11, a.m. | 105 | 35 | 2.00 | — | 105 | 35 | 2.00 | — |
| Day 11, p.m. | 79 | 26 | 1.50 | — | 79 | 79 | — | 2.25 |
| Day 12, a.m. | 53 | 18 | 1.00 | — | 53 | 53 | — | 1.50 |
| Day 12, p.m. | 24 | 8 | 0.45 | — | 24 | 24 | — | 0.70 |
| Day 13, a.m. | 24 | 8 | 0.45 | — | 24 | 24 | — | 0.70 |
| Total | 705 | 235 | 13.40 | — | 705 | 353.5 | 10.00 | 5.15 |
1
The low LH and high LH treatments were prepared using 2 drugs: Pluset (50% LH, 50% FSH; Minitube of America, Verona, WI) and Flex H (25% LH, 75% FSH; Minitube of America) in different doses. The first 4 injections of the 8-injection protocol were identical; the last 4 injections were varied to accommodate the low LH/high LH treatments.