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. Author manuscript; available in PMC: 2018 Sep 5.
Published in final edited form as: Nat Genet. 2018 Mar 5;50(3):401–413. doi: 10.1038/s41588-018-0064-5

Figure 1.

Figure 1

Epistasis between SNPs at FUT2 and ABO (n=94,674). SNP rs601338, determines secretor status; Se/Se and Se/se are secretors (dominant), and se/se are non-secretors. SNP rs2519093 at ABO, C allele is recessive. (A) Residual LDL by genotype combination, where the vertical line represents 95% confidence intervals. (B) ABO locus plot for secretors (Se/Se or Se/se), around rs2519093 (linear regression on LDL). (C) ABO locus plot for non-secretors around rs2519093 (linear regression on LDL). All tests are two-sided.