Table 5.
Functional information of ALDH2 rs671 and CYP2E1 rs2031920 genetic polymorphisms
| Gene site | FS score | Functional category | Prediction tool | Prediction result |
|---|---|---|---|---|
| ALDH2 | 0.856 | Protein coding | PolyPhen | Probably damaging |
| rs671 | SIFT | Damaging | ||
| SNP effect | Benign | |||
| LS-SNP | Benign | |||
| SNPs3D | Deleterious | |||
| Ensembl-NS | Nonsynonymous | |||
| Splicing regulation | ESEfinder | Changed | ||
| ESRSearchi | Changed | |||
| PESX | Changed | |||
| RESCUE_ESE | Changed | |||
| Post translation | OGPET | Not exist | ||
| Sulfinator | Not exist | |||
| CYP2E1 | 0.398 | Transcriptional regulation | Ensembl-NS | Frameshift coding |
| GoldenPath | Not exist | |||
| Ensembl-TR | Regulatory region |
Abbreviation: FS, functional significance.