Table 2.
Comparison of demographic, clinicopathologic, and laboratory data in low and high NLR groups
| Variables | Total, n=109 | Low NLR group, n=34 | High NLR group, n=75 | p |
|---|---|---|---|---|
| Age (years), median (range) | 66 (18–82) | 64 (21–81) | 66 (18–82) | 0.341 |
| Sex, n (%) | ||||
| Male | 65 (59.6) | 19 (55.9) | 46 (61.3) | 0.675 |
| Female | 44 (40.4) | 15 (44.1) | 29 (38.7) | |
| ASA, n (%) | ||||
| I/II | 62 (56.9) | 18 (52.9) | 44 (58.7) | 0.677 |
| III/IV | 47 (43.1) | 16 (47.1 | 31 (41.3) | |
| Cirrhosis, n (%) | ||||
| No | 47 (43.1) | 18 (52.9) | 29 (38.7) | 0.211 |
| Yes | 62 (56.9) | 16 (47.1) | 46 (61.3) | |
| Etiology, n (%) | ||||
| HBV | 30 (27.5) | 8 (23.5) | 22 (29.3) | 0.668 |
| HCV | 23 (21.1) | 5 (14.7) | 18 (24) | |
| Alcohol abuse | 6 (5.5) | 2 (5.9) | 4 (5.3) | |
| Others | 3 (2.8) | 1 (2.9) | 2 (2.7) | |
| Child-Pugh score, n (%) | ||||
| A | 47 (75.8) | 12 (35.3) | 35 (46.7) | 0.377 |
| B | 15 (24.2) | 4 (11.8) | 11 (14.7) | |
| WBC (×109/L), median (range) | 6.7 (2.2–20.4) | 5.6 (2.2–20.4) | 7.1 (2.8–14.2) | 0.045 |
| Platelet (×109/L), median (range) | 210 (42–583) | 192 (91–427) | 233 (42–583) | 0.021 |
| Total bilirubin (mmol/L), median (range) | 12.5 (3.6–636) | 12.5 (3.6–636) | 12.5 (5.2–115) | 0.392 |
| ALT (IU/L), median (range) | 32 (6–166) | 32 (6–116) | 30 (6–166) | 0.753 |
| γGT (IU/L), median (range) | 59 (9–1185) | 59 (14–1185) | 58.5 (9–470) | 0.154 |
| Lesion number, n (%) | ||||
| Single | 95 (87.2) | 31 (91.2) | 64 (85.3) | 0.542 |
| Multiple | 14 (12.8) | 3 (8.8) | 11 (14.7) | |
| Major lesion size, n (%) | ||||
| <5 cm | 12 (11) | 5 (14.7) | 7 (9.3) | 0.51 |
| ≥5 cm | 97 (89) | 29 (85.3) | 68 (90.7) | |
| Hepatectomy, n (%) | ||||
| Anatomic | 52 (47.7) | 17 (50) | 35 (46.7) | 0.837 |
| Nonanatomic | 57 (52.3) | 17 (50) | 40 (53.3) | |
| Extent of resection, n (%) | ||||
| Major | 39 (35.8) | 9 (26.5) | 30 (40) | 0.2 |
| Minor | 70 (64.2) | 25 (73.5) | 45 (60) | |
Note: Values shown in bold indicate a statistically significant difference between the groups (p<0.05).
Abbreviations: γGT, gamma-glutamyl transferase; ALT, alanine aminotransferase; ASA, American Society of Anesthesiologists; HBV, hepatitis B virus; HCV, hepatitis C virus; NLR, neutrophil-to-lymphocyte ratio; WBC, white blood cells.