Table 4.
Univariate and multivariate analyses of prognostic factors
| Variable | Univariate analysis
|
Multivariate analysis
|
||||
|---|---|---|---|---|---|---|
| HR | 95%CI | p | HR | 95%CI | p | |
| Sex (female) | 1.187 | 0.749–1.879 | 0.466 | |||
| Age (≥65 years) | 1.118 | 0.708–1.766 | 0.632 | |||
| HBV | 1.329 | 0.819–2.159 | 0.25 | |||
| HCV | 1.566 | 0.931–2.635 | 0.091 | |||
| Cirrhosis | 1.986 | 1.234–3.195 | 0.005 | 1.509 | 0.9–2.532 | 0.119 |
| Child-Pugh (B) | 2.094 | 1.118–3.922 | 0.021 | 1.856 | 0.948–3.636 | 0.071 |
| Platelets (<100×109/L) | 5.394 | 2.049–14.203 | 0.001 | 5.050 | 1.861–13.702 | 0.001 |
| Bilirubin (≥25 µmol/L) | 1.068 | 0.462–2.465 | 0.878 | |||
| ALT (≥39 IU/L) | 1.411 | 0.893–2.229 | 0.141 | |||
| γGT (≥55 IU/L) | 0.919 | 0.583–1.447 | 0.715 | |||
| NLR (≥1.28) | 1.919 | 1.124–3.276 | 0.017 | 1.865 | 1.086–3.203 | 0.024 |
| Tumor number (multiple) | 1.397 | 0.717–2.721 | 0.326 | |||
| Major lesion size (≥5 cm) | 1.688 | 0.730–3.899 | 0.221 | |||
| Nonanatomic hepatectomy | 0.807 | 0.513–1.267 | 0.351 | |||
| Intraoperative transfusion | 1.269 | 0.549–2.931 | 0.577 | |||
| Major resection (≥segments) | 1.382 | 0.865–2.209 | 1.176 | |||
Note: Values shown in bold indicate a statistically significant difference between the groups (p<0.05).
Abbreviations: γGT, gamma-glutamyl transferase; ALT, alanine aminotransferase; HBV, hepatitis B virus; HCV, hepatitis C virus; NLR, neutrophil-to-lymphocyte ratio.