Table 3.
Data sets | ACCORD | AFFIRM | BARI 2D | ARIC | JHS | FHS cohort |
FHS offspring |
FHS Gen3 |
FOCUS | MRFIT | ALL HAT |
BHS | CORAL | NGHS | OMNI heart |
POWER-UP | SPRINT-POP |
Any T2DM medication | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | |
Insulin | + | + | + | + | + | + | + | + | + | + | + | + | |||||
Oral medications | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | |
Biguanides | + | + | + | + | + | + | |||||||||||
Sulfonylureas | + | + | + | + | + | + | |||||||||||
Meglitinides | + | + | + | + | + | ||||||||||||
Alpha-glucosidase inhibitors | + | ||||||||||||||||
Thiazolidinediones | + | + | + | + | + | + | |||||||||||
DPP4 inhibitor | + | ||||||||||||||||
Incretin mimetic | + | ||||||||||||||||
Any dyslipidaemia medication | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Statins | + | + | + | + | + | + | + | + | + | + | + | + | |||||
Fibrates | + | + | + | + | + | + | + | ||||||||||
Niacin and nicotinic acid | + | + | + | + | + | + | + | ||||||||||
Any CVD medication | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Aspirin | + | + | + | + | + | + | + | + | + | + | + | ||||||
Other inhibitors of platelet aggregation/anticoagulant | + | + | + | + | + | + | + | + | + | ||||||||
Diuretic | + | + | + | + | + | + | + | + | + | + | |||||||
ACE inhibitor | + | + | + | + | + | + | + | + | + | + | |||||||
ARB | + | + | + | + | + | + | + | + | |||||||||
Beta blocker | + | + | + | + | + | + | + | + | + | + | + | ||||||
Calcium channel blocker | + | + | + | + | + | + | + | + | |||||||||
Peripheral alpha blocker | + | + | + | + | + | + | + | + | |||||||||
Central alpha-adrenergic agonist | + | + | + | + | + | + | + | + | |||||||||
Nitrates | + | + | + | + | + | + | + | + | + | ||||||||
Antiarrhythmic | + | + | + | + | + | + | + | + | |||||||||
Potassium supplements | + | + | + | + | + | + | + | + | |||||||||
Any endocrine/metabolic medication | + | + | + | + | + | + | + | + | |||||||||
Progestin/oestrogens/ birth control pills |
+ | + | + | + | + | + | + | ||||||||||
Glucocorticoids | + | ||||||||||||||||
Androgens | + |
ACCORD, Action to Control Cardiovascular Risk in Diabetes; AFFIRM, Atrial Fibrillation Follow-Up Investigation of Rhythm Management; ALLHAT, Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial; ARB, angiotensin receptor blockers; ARIC, Atherosclerosis Risk in Communities; BARI 2D, Bypass Angioplasty Revascularization Investigation in Type 2 Diabetes; BHS, Bogalusa Heart Study; CORAL, Cardiovascular Outcomes in Renal Atherosclerotic Lesions; CVD, cardiovascular disease; DPP4, dipeptidyl peptidase 4; FHS, Framingham Heart Study; FOCUS, Functional Outcomes in Cardiovascular Patients Undergoing Surgical Hip Fracture Repair; JHS, Jackson Heart Study; MRFIT, Multiple Risk Factor Intervention Trial for the Prevention of Coronary Heart Disease; NGHS, NHLBI Growth and Health Study; OMNI heart, Optimal Macronutrient Intake Trial to Prevent Heart Disease; POWER-UP, Practice Based Opportunities for Weight Reduction Trial at the University of Pennsylvania; SPRINT-POP, Systolic Blood Pressure Intervention Trial Primary Outcome Paper; T2DM, type 2 diabetes mellitus.