Table 3.

Multiple linear regression model predicting 1-year glycated hemoglobin A1c (HbA1c) change as a function of medication possession ratio (MPR), stratified by oral antihyperglycemic agent (OHA) therapy cohort

	Multivariate model
	Value	SE	t-value	p-value
OHA monotherapy
Change in HbA1c (%)
MPR (%)	−0.892	0.076	−11.680	0.000
Constant	−0.002	0.073	−0.030	0.974
MPR (%)
Age (years)	0.002	0.000	10.110	0.000
Change in BMI (kg/m2)	−0.003	0.001	−2.760	0.006
Baseline HbA1c (%)	−0.002	0.002	−1.400	0.162
Change in total cholesterol	−0.016	0.002	−7.270	0.000
Constant	0.827	0.019	42.780	0.000
OHA dual therapy
Change in HbA1c (%)
MPR (%)	−0.859	0.155	−5.550	0.000
Constant	−0.133	0.143	−0.930	0.353
MPR (%)
Age (years)	0.002	0.000	6.320	0.000
Change in BMI (kg/m2)	0.004	0.001	2.420	0.015
Baseline HbA1c (%)	−0.007	0.002	−3.400	0.001
Change in total cholesterol	−0.012	0.003	−4.230	0.000
Constant	0.874	0.023	37.300	0.000
OHA triple therapy
Change in HbA1c (%)
MPR (%)	−2.058	0.348	−5.920	0.000
Constant	0.840	0.319	2.630	0.009
MPR (%)
Age (years)	0.001	0.001	2.170	0.031
Change in BMI (kg/m2)	−0.001	0.004	−0.220	0.823
Baseline HbA1c (%)	−0.013	0.005	−2.610	0.009
Change in total cholesterol	−0.016	0.008	−1.930	0.054
Constant	0.941	0.063	15.050	0.000

BMI, body mass index.