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. 2018 May 9;8(5):e019735. doi: 10.1136/bmjopen-2017-019735

Table 3.

ROC curve analysis of baseline anthropometric indices for predicting future hyperglycaemia

AUC SE P values 95% CI Cut-off point Youden’s value Sensitivity, % Specificity, % DeLong’s test (p values)
WHtR (cm/cm) BMI (kg/m2) Waist circumference (cm) WHR (cm/cm)
Isolated IFG
 WHtR (cm/cm) 0.578 0.025 0.002 (0.529 to 0.626) 0.51 0.151 54.90 60.19 0.010 0.201 0.611
 BMI (kg/m2) 0.544 0.025 0.081 (0.495 to 0.593) 21.36 0.078 80.40 27.43 0.010 0.023 0.421
 Waist circumference (cm) 0.592 0.024 0.000 (0.545 to 0.639) 77.10 0.148 71.24 43.54 0.201 0.023 0.195
 Women 0.584 0.031 0.010 (0.524 to 0.644) 75.00 0.166 74.44 42.11
 Men 0.579 0.041 0.050 (0.526 to 0.631) 87.00 0.165 49.21 67.24
 WHR (cm/cm) 0.567 0.026 0.008 (0.537 to 0.597) 0.88 0.128 47.06 65.71 0.611 0.421 0.195
 Women 0.568 0.033 0.036 (0.504 to 0.632) 0.85 0.140 57.78 56.19
 Men 0.525 0.042 0.534 (0.471 to 0.578) 0.90 0.095 53.97 55.52
Isolated IGT
 WHtR (cm/cm) 0.634 0.017 0.000 (0.600 to 0.667) 0.51 0.214 62.24 59.12 0.003 0.006 0.000
 BMI (kg/m2) 0.591 0.018 0.000 (0.556 to 0.627) 22.68 0.155 68.88 46.64 0.003 0.178 0.223
 Waist circumference (cm) 0.610 0.017 0.000 (0.576 to 0.645) 78.00 0.197 71.90 47.81 0.006 0.178 0.001
 Women 0.635 0.021 0.000 (0.593 to 0.676) 78.00 0.260 68.42 57.59
 Men 0.542 0.032 0.174 (0.480 to 0.605) 87.80 0.132 43.44 69.76
 WHR (cm/cm) 0.567 0.018 0.000 (0.539 to 0.594) 0.86 0.123 61.63 50.64 0.000 0.223 0.001
 Women 0.587 0.022 0.000 (0.544 to 0.630) 0.82 0.154 77.03 38.39
 Men 0.524 0.032 0.433 (0.463 to 0.586) 0.89 0.098 57.38 52.41
IFG+IGT
 WHtR (cm/cm) 0.713 0.022 0.000 (0.670 to 0.755) 0.53 0.351 62.33 72.79 0.106 0.556 0.026
 BMI (kg/m2) 0.685 0.022 0.000 (0.642 to 0.729) 23.38 0.316 77.40 54.22 0.106 0.254 0.492
 Waist circumference (cm) 0.706 0.021 0.000 (0.665 to 0.748) 79.80 0.351 82.88 52.19 0.556 0.254 0.032
 Women 0.732 0.026 0.000 (0.682 to 0.783) 79.80 0.420 79.57 62.38
 Men 0.656 0.039 0.000 (0.579 to 0.733) 90.30 0.242 43.40 80.76
 WHR (cm/cm) 0.667 0.022 0.000 (0.638 to 0.695) 0.87 0.274 69.18 58.23 0.026 0.492 0.032
 Women 0.686 0.027 0.000 (0.633 to 0.739) 0.83 0.312 86.02 45.20
 Men 0.631 0.038 0.003 (0.556 to 0.705) 0.92 0.261 54.72 71.38
NDDM
 WHtR (cm/cm) 0.730 0.017 0.000 (0.696 to 0.764) 0.52 0.366 74.21 62.43 0.000 0.001 0.010
 BMI (kg/m2) 0.677 0.020 0.000 (0.639 to 0.716) 24.32 0.315 64.68 66.81 0.000 0.093 0.596
 Waist circumference (cm) 0.700 0.018 0.000 (0.665 to 0.735) 78.00 0.292 81.35 47.81 0.001 0.093 0.429
 Women 0.714 0.021 0.000 (0.673 to 0.756) 77.10 0.344 81.76 52.63
 Men 0.686 0.033 0.000 (0.622 to 0.750) 88.00 0.298 56.99 72.85
 WHR (cm/cm) 0.688 0.018 0.000 (0.661 to 0.715) 0.88 0.304 67.73 62.71 0.010 0.596 0.429
 Women 0.696 0.022 0.000 (0.653 to 0.738) 0.84 0.301 79.75 50.31
 Men 0.681 0.030 0.000 (0.622 to 0.740) 0.92 0.299 60.22 69.66

AUC, area under curve; BMI, body mass index; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; NDDM, newly diagnosed diabetes mellitus; ROC, receiver operating characteristic; WHR, waist-to-hip ratio; WHtR, waist-to-height ratio.