Table 4.
Odds of Symptoms by SNPs Adjusted for Maternal Age and Parity.
| Symptom | Gene SNP | Association | OR | 95% CI | p Value |
|---|---|---|---|---|---|
| Headaches | CFH rs1329428 | C/T vs. C/C | 0.24 | [0.089, 0.616] | .003 |
| CFH rs1329428 | C/T + T/T vs. C/C | 0.25 | [0.099, 0.649] | .004 | |
| Visual disturbances | CFH rs1329428 | C/T vs. C/C | 0.38 | [0.153, 0.918] | .03 |
| CFH rs1329428 | C/T + T/T vs. C/C | 0.43 | [0.185, 0.987] | .05 | |
| S100A8 rs3795391 | C/C + C/T vs. T/T | 0.07 | [0.009, 0.541] | .01 | |
| F11R rs7546890 | C/T + T/T vs. C/C | 0.36 | [0.144, 0.887] | .03 | |
| Fatigue/tiredness | S100A8 rs3795391 | C/C + TT vs.T/T | 0.28 | [0.096, 0.821] | .02 |
| Nausea and/or vomiting | S100A8 rs3795391 | C/C + TT vs.T/T | 0.34 | [0.122, 0.953] | .04 |
| FSTL3 rs1046253 | G/A vs. A/A | 12.8 | [1.249, 130.191] | .03 | |
| Indigestion/heartburn | F11R rs11265544 | C/C vs. A/A | 5.4 | [1.065, 27.754] | .04 |
| Palpitations | F11R rs836 | A/G vs. A/A | 0.04 | [0.004, 0.509] | .01 |
| Shortness of breath | F11R rs836 | A/A + A/G vs. G/G | 2.3 | [1.014, 5.170] | .05 |
| FSTL3 rs28364866 | T/C + T/T vs. C/C | 2.5 | [1.033, 6.218] | .04 | |
| Back pain | CFH rs10922096 | C/T + T/T vs. C/C | 0.37 | [0.154, 0.887] | .03 |
| Chest pain | CFH rs10922096 | C/T + T/T vs. C/C | 0.28 | [0.091, 0.884] | .03 |
Note. CI = confidence interval; OR = odds ratio; SNP = single-nucleotide polymorphism.