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Modular domain structure of cyclosporin synthetases and six most similar nonribosomal peptide synthetases. Codes above modules are A-domain specificities of NRPS. Blue modules belong to group 1 based on phylogenetic analysis in Fig. 6. Red amino acids are the final products of the sixth A-domain of cyclosporin synthetases and the corresponding nearest A-domains of six other synthetases. Me, N-methyl
