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Percentage of vaccine participants who seroconverted by 1 month following vaccination determined by different ELISAs.
| ELISA type | rChAd3 EBO Z responders (%) N=487 |
rVSVΔG-ZEBOV responders (%) N=484 |
Placebo N=491 |
|---|---|---|---|
| FANG | 250 (51.3%) | 358 (74.0%) | 19 (3.9%) |
| ADI | 150 (30.8) | 167 (34.5%) | 29 (5.9%) |
ELISA, enzyme-linked immunosorbent assay, FANG, Filovirus Animal Nonclinical Group. Seroconversion cutoffs for the FANG and ADI ELISAs were 607 and 840 EU/ml, respectively.
