Table 3. Unadjusted and adjusted odd ratio (OR) and 95% confidence interval (CI) for the association of metabolic syndrome and its individual component with the presence of CKD.
Methods | Unadjusted | Model 1 | Model 2 | |||
---|---|---|---|---|---|---|
OR (95% CI) |
P | OR (95% CI) |
P | OR (95% CI) |
P | |
The presence of MetS and its individual component† | ||||||
-Metabolic syndrome* | 1.13 (1.06–1.20) |
<0.001 | 1.15 (1.07–1.24) |
<0.001 | 1.14 (1.06–1.22) |
<0.001 |
-WC >90 cm in men and >80 cm in women | 0.97 (0.92–1.03) |
0.29 | 0.99 (0.93–1.05) |
0.68 | 0.97 (0.92–1.04) |
0.52 |
-blood pressure ≥ 130/85 mmHg | 2.39 (2.19–2.62) |
<0.001 | 1.57 (1.43–1.73) |
<0.001 | 1.55 (1.40–1.70) |
<0.001 |
-serum triglyceride level ≥ 150 mg/dL | 1.41 (1.34–1.48) |
<0.001 | 1.65 (1.57–1.75) |
<0.01 | 1.65 (1.56–1.74) |
<0.001 |
-serum HDL-C <40 mg/dL in men and <50 mg/dL in women | 1.36 (1.29–1.42) |
<0.001 | 1.34 (1.29–1.43) |
<0.01 | 1.35 (1.28–1.42) |
<0.001 |
BMI, body mass index; HDL-C, high density lipoprotein cholesterol; WC, waist circumference. Model 1 adjusted for age and sex. Model 2 further adjusted for comorbidities (coronary artery disease, cerebrovascular disease, left ventricular hypertrophy, and peripheral arterial disease).
*metabolic syndrome was defined as having elevated waist circumference (>90 and >80 cm in men and women, respectively) plus any 2 of the followings: triglyceride>150 mg/dL, HDL<40 in men or <50 mg/dL in women or receiving lipid-lowering drugs, BP≥130/85 mmHg or receiving anti-hypertensive drugs, and blood sugar ≥100 mg/dL or being diagnosed with diabetes mellitus.
†Since all patients were type2 diabetes, we did not analyze the ORs for elevated plasma glucose criterion of metabolic syndrome.