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. 2018 May 9;14(5):e1007312. doi: 10.1371/journal.pgen.1007312

Fig 4. CLR-1/RPTP is sufficient to drive increased synaptogenesis.

Fig 4

(A) Representative schematics and micrographs of NLG-1 GRASP fluorescence labeling PHB-AVA synapses in wild-type animals and animals overexpressing clr-1/RPTP in AVA neurons (pAVA::clr-1/RPTP OE). (B) Quantification of NLG-1 GRASP fluorescence. Overexpression of clr-1/RPTP in AVA neurons results in increased NLG-1 GRASP fluorescence (n>100). Two lines were examined with this transgene, and combined in the graph above. Values for each individual transgenic line are included in S2 Table. ***P<0.001, U-test, comparison to wild-type. 95% confidence intervals for the medians are included in S1 Table. (C) Overexpression of clr-1/RPTP in AVAs results in a faster behavioral response (n = 80). *P<0.05, t-test, comparison to wild-type. Error bars are SEM.