Table 1. Baseline anthropometric and pulmonary function characteristics for participants with CF and age-matched control children.
| CF group (n = 9) | Healthy group (n = 18) | p-value | |
|---|---|---|---|
| Anthropometric variables | |||
| Gender ratio, M/F % | 44/56 | 39/61 | NA |
| Age years | 13.3 (±2.4) | 13.8 (±1.8) | 0.59 |
| Height cm | 159.8 (±14) | 156.8 (±8.4) | 0.50 |
| Weight kg | 46.7 (±13.4) | 51 (±7.2) | 0.28 |
| BMI kg/m2 | 18.0 (±2.7) | 20.7 (±2.6) | 0.02 |
| Lung function | |||
| FVC L | 2.6 (±1.3) | 3.3 (±0.6) | 0.06 |
| FVC % predicted value | 72.1 (±24.3) | 99.5 (±14.2) | 0.001 |
| FEV1 L | 2.0 (±1.0) | 3.0 (±0.9) | 0.07 |
| FEV1% predicted value | 66.0 (±24) | 106.7 (±30) | 0.001 |
| MIP cmH2O | 93.6 (±34.3) | 109.3 (±23.07) | 0.16 |
| MEP cmH2O | 110.8 (±33.6) | 127 (±25.27) | 0.28 |
| Cardio-respiratory variables (before walking test) | |||
| MV L/min | 8.1 (±2.8) | 7.6 (±2.3) | 0.48 |
| RR cpm | 14.8 (±3.7) | 13.5 (±3.4) | 0.39 |
| VO2 mL/min | 276.8 (±89.1) | 283.2 (±51.3) | 0.64 |
| VCO2 mL/min | 208.4 (±69.4) | 252.4 (±40.1) | 0.09 |
| Cardio-respiratory variables (after 2min warm-up) | |||
| MV L/min | 8.4 (±2.9) | 7.8 (±1.9) | 0.45 |
| RR cpm | 15.2 (±3.4) | 13.6 (±3.2) | 0.28 |
| VO2 post warm-up mL/min | 309.3 (±94.8) | 289.2 (±57.1) | 0.74 |
| VCO2 post warm-p mL/min | 269.4 (±78.6) | 260.2 (±52.9) | 0.61 |
Abbreviations: BMI: body mass index; CF: cystic fibrosis; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; MEP: maximal expiratory pressure; MIP: maximal inspiratory pressure; MV: minute ventilation; RR: respiratory rate; VCO2: carbon dioxide production; VO2: oxygen consumption. Values are expressed as mean (±standard deviation).