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. 2018 May 9;13(5):e0196750. doi: 10.1371/journal.pone.0196750

Table 2. Backpack carrying modified lung function at rest and cardio-respiratory variables while walking in the CF group.

Central values Mean differences
NB BB UB NB vs BB
95% CI
NB vs UB
95% CI
BB vs UB
95% CI
FVC L 2,37 (2,62) 2,24 (2,53) 2,30 (2,30) NA NA NA
FVC % 72.1 (±24.3) 69.5 (±21.5) 68.5 (±23.3)* -2.6 [-5.9 to 0.6] -3.6 [-6.9 to -0.4] -1 [-4.3 to 2.3]
FEV1 L 1,90 (2,09) 1,84 (2,08) 1,67 (1,93)* § NA NA NA
FEV1% 66.6 (±23.7) 64.5 (±23.1) 59.9 (±21.8)*§ -2.1 [-5.4 to 1.1] -6.7 [-10 to -3.5] -4.6 [-7.8 to 1.3]
PEF L/min 4.2 (±2.0) 4.1 (±2.0) 3.9 (±2.2) -0.1 [-0.5 to 0.4] -0.4 [-0.9 to 0.1] -0.3 [-0.8 to 0.2]
MIP cmH2O 93.6 (±34.3) 91.3 (±38.2) 81.0 (±31.4)* -2.4 [-14.9 to 9.9] -12.6 [-25 to -0.4] -10.3 [-22.5 to 2]
MEP cmH2O 110.8 (±33.6) 99.3 (±32.2) 93.4 (±23.3)* -11.5 [-28.1 to 5.1] -17.4 [-34 to -0.8] -5.9 [-22.4 to 10.7]
MV L/min 19.7 (±6.3) 21.4 (±6.6) ε 23.3 (±6.8)*§ +1.7 [0.0 to 3.3] +3.6 [2 to 5.3] +2 [0.3 to 3.6]
Dyspnea Borg 0.5 (0) 1.0 (1.0) 3.0 (2.0)* NA NA NA
RR cpm 19.6 (3.8) 20.6 (8.0) 22.5 (9.9)* NA NA NA
VO2 mL/min 622.5 (±237.4) 658.4 (±234) ε 708.2 (±245) *§ +35.9 [10.3 to 61.5] +85.7 [60.1 to 111] +49.8 [24.2 to 75.4]
VCO2 mL/min 404.9 (±191.4) 435.7 (±190) 465.9 (±202)* +30.7 [-23 to 84.5] +61 [7.3 to 114.7] +30.3 [-23.4 to 84]

Abbreviations: BB: bilateral backpack carrying; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; MEP: maximal expiratory pressure; MIP: maximal inspiratory pressure; MV: minute ventilation; NB: no backpack carrying; PEF: peak expiratory flow; RR: respiratory rate; UB: unilateral backpack carrying; VCO2: carbon dioxide production; VO2: oxygen consumption. Central values are expressed as mean (±SD) or median (IQR) and mean differences (when applicable) between backpack carrying positions are expressed as Mean [95% CI]

* indicates a statistically significant difference between NB and UB with p<0.05

§ indicates a statistically significant difference between BB and UB with p<0.05

ε indicates a statistically significant difference between NB and BB with p<0.05. All these p-values are indicated for post-hoc analyses after multiple analysis of variance (MANOVA).