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. 2018 May 9;13(5):e0196948. doi: 10.1371/journal.pone.0196948

Table 2. Number of positive goats to each IFN-γ release assay.

Antigen Group Week
0 3 5 8
C S C S C S C S
PPD-Bb Control 0/8 0/8 0/8 0/8 0/8 0/8 0/8 0/8
BCG 0/8 0/8 2/8 5/8 4/8 6/8 1/8 5/8
HIMB 0/8 0/8 1/8 2/8 4/8 4/8 3/8 3/8
ECc Control 0/8 0/8 0/8 0/8
BCG 0/8 0/8 0/8 0/8
HIMB 0/8 0/8 0/8 0/8
Week
11 13 15 17a
C S C S C S C S
PPD-Bb Control 8/8 8/8 8/8 8/8 8/8 8/8 5/7 6/7
BCG 8/8 8/8 8/8 8/8 8/8 8/8 8/8 8/8
HIMB 6/7 6/7 7/7 7/7 6/7 7/7 7/7 7/7
ECc Control 8/8 8/8 8/8 8/7
BCG 8/8 8/8 8/8 8/8
HIMB 7/7 7/7 6/7 7/7

Animals were vaccinated at week 0 and challenged at week 8.

a One goat of the Control group was euthanized at week 16.

b PPD-B, M. bovis purified protein derivative; two criteria were used for positivity: C, Conservative (S/P ≥ 35%), and S, Stringent (S/P ≥ 16%).

c EC, ESAT-6/CFP-10 protein mixture; the criterion for positivity was S/P ≥ 16%.