Table 1. Treatments administered by each study and respective study characteristics for included efficacy studies.
Reference no. | Study | IVM + ALB | ALB alone (or with placebo) | IVM alone (or with placebo) | Country | Studied parasites | Follow-up period | Age group | No. stool samples |
---|---|---|---|---|---|---|---|---|---|
[18] | Belizario et al., 2003 | X | X | X | Philippines |
T. trichiura A. lumbricoides |
7–14 days | 6–12 | 1 at baseline 1 at follow-up |
[19] | Ismail et al., 1999 | X | X | Sri Lanka | T. trichiura | 3 weeks | 4–14 | 1 at baseline 1 at follow-up |
|
[20] | Knopp et al., 2010 | X | X | Tanzania |
T. trichiura A. lumbricoides Hookworm |
22–39 days | 6–20 | 2 at baseline 2 at follow-up |
|
[24] | Speich et al., 2015* | X | Tanzania |
T. trichiura A. lumbricoides Hookworm |
18–23 days | 6–14 | 2 at baseline 2 at follow-up |
Note: IVM + ALB = co-administration of ivermectin-albendazole, ALB = albendazole, IVM = ivermectin.
*Speich et al. 2015 [24] compared ivermectin-albendazole to albendazole-mebendazole, albendazole-oxantel pamoate and mebendazole alone.