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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Neuroscience. 2018 Apr 9;380:1–13. doi: 10.1016/j.neuroscience.2018.03.045

Figure 5. Neurobehavioral outcomes after ischemic stroke.

Figure 5

(A–B) Forelimb placing and spontaneous limb use, showing deficits in contralateral placing and limb use responses in both stroke groups at 7d post-ischemia; however, by 30d only the juvenile mice had returned to baseline levels, while adult mice showed continued impairment. (C) Composite score of overall impairment of the affected limb and general motor response measures, showing reduced limb function at 7d post-injury and recovery of functioning at 30d only in juvenile mice. (D) The corner test detected postural bias in both MCAo-injured adult and juvenile mice between baseline and 7d, but only adult mice had extended functional impairments at 30d.