Figure 3. Characterization of skin T_RM cells after cutaneous C. albicans infection.

(A) Expression of CD103 and CD69 in KAEDE-red and KAEDE-green CD4 and CD8 T cells (gated on CD3⁺CD4⁺ and CD3⁺CD8⁺ cells) from infected ear skin of KAEDE mice at day 60 after candida infection before (left), immediately (0 h, middle), and 24 hours (24 h, right) after violet light exposure. (B) Expression of CD103 and CD69 in KAEDE-red (left) and KAEDE-green (right) CD4 and CD8 T cells (gated on CD3⁺CD4⁺ and CD3⁺CD8⁺ cells) from infected ear skin of KAEDE mice at day 60 after candida infection 24 hours after violet light exposure. Data are representative of five independent experiments (A and B). (C) Expression of IL-17 in KAEDE-red (left) and KAEDE-green (middle) CD4 and CD8 T cells (gated on CD3⁺CD4⁺ and CD3⁺CD8⁺ cells) from infected ear skin (right) of KAEDE mice at day 30 after candida infection 24 hours after violet light exposure. Data are representative of four independent experiments. (D) The percentage of IL-17-producing KAEDE-red and KAEDE-green CD4 T cells from infected ear skin (n = 4) at day 30 after candida infection. The lines indicate the mean. *** p < 0.001.