Table 1.
Expression of axon guidance, signaling, and adhesion molecules in the OE and OB
| Gene | Name | Function | OE | OB | M/T dendrites |
|---|---|---|---|---|---|
| (mRNA) | (mRNA) | (Protein) | |||
| ephA5 | Ephrin type-A receptor 5 | Protein-tyrosine kinase | + | − | − |
| efna5 | ephrin-A5 | Ligand of Eph-related Kinase | + | + | − |
| s100A5 | S100 calcium binding protein A5 | Calcium binding | + | − | − |
| kirrel2 | kin of IRRE like 2 | Cell adhesion | + | − | − |
| kirrel3 | kin of IRRE like 3 | Cell adhesion | + | + | − |
| pcp4 | Purkinje cell protein 4 | Calmodulin binding | + | − | − |
| ptprn | protein tyrosine phosphatase type-N receptor | Signal transduction | + | + | − |
| ptprf | protein tyrosine phosphatase type-F receptor | Signal transduction | + | − | − |
| nrp1 | neuropilin 1 | Signal transduction | + | + | − |
| nrp2 | neuropilin 2 | Signal transduction | + | + | − |
| nph3 | neurexophilin 3 | Neuropeptide | + | − | − |
| sema3a | semaphorin 3a | Axon guidance | + | + | − |
| sema3f | semaphorin 3f | Axon guidance | + | − | − |
| sema4d | semaphorin 4d | Axon guidance | − | + | − |
| sema7a | semaphorin 7a | Axon guidance | + | + | − |
| plxna1 | plexin a1 | Signal transduction | + | − | − |
| plxna2 | plexin a2 | Signal transduction | − | − | − |
| plxna3 | plexin a3 | Signal transduction | + | + | − |
| plxna4 | plexin a4 | Signal transduction | − | − | − |
| plxnb1 | plexin b1 | Signal transduction | + | − | − |
| plxnb2 | plexin b2 | Signal transduction | + | − | − |
| plxnb3 | plexin b3 | Signal transduction | + | − | − |
| plxnc1 | plexin c1 | Signal transduction | − | + | + |
| ingb1 | integrin beta 1 | Cell adhesion | − | − | − |
| omp | olfactory marker protein | Signal transduction | + | − | − |
| pcdh21 | protocadherin-21 | Cell adhesion | − | + | + |
OE and OB sections at P4 were analyzed by in situ hybridizaion, OB sections were analyzed by immunohistochemistry. +, detected; −, not detected