Fig. 8. miR-338-3p suppresses peritoneal dissemination of GC in vivo by targeting PTP1B.

a,b MKN45-Luc cells (5 × 10⁶ cells) infected with control lentivirus, miR-338-3p lentivirus, PTP1B plasmid, or miR-338-3p lentivirus plus PTP1B plasmid were injected into the left lower peritoneal cavity (i.p.) of nude mice (10 mice per group). Bioluminescence images of tumors were detected on day 1, 7, 14, and 21 after implantation of GC cells. a Representative images; b quantitative analysis. n = 10 mice per group; data are represented as mean ± SEM; *p < 0.05; two-tailed Student’s t-test