. 2018 May 9;8:7306. doi: 10.1038/s41598-018-25674-4

Table 2.

Identified possible substrates for TG2 using pepT26.

Accession number	Name	Days
Accession number	Name	0	3	7	14
O08756	3-hydroxyacyl-CoA dehydrogenase type-2		+	+	+
P20060	β-hexosaminidase subunit β		+	+	+
P05064	Fructose-bisphosphate aldolase A		+	+	+
Q91Y97	Fructose-bisphosphate aldolase B		+	+	+
P54071	Isocitrate dehydrogenase [NADP], mitochondrial		+	+	+
P51660	Peroxisomal multifunctional enzyme type 2		+	+	+
P31725	Protein S100-A9		+	+	+
P26040	Ezrin		+	+
P06909	Complement factor H		+		+
P63017	Heat shock cognate 71 kDa protein		+		+
O35737	Heterogeneous nuclear ribonucleoprotein H		+		+
Q61781	Keratin, type I cytoskeletal 14		+		+
P08071	Lactotransferrin		+		+
P45952	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial		+		+
P26041	Moesin		+		+
Q99MZ7	Peroxisomal trans-2-enoyl-CoA reductase		+		+
Q9WUA2	Phenylalanyl-tRNA synthetase β chain		+		+
P84104	Splicing factor, arginine/serine-rich 3		+		+
P26443	Glutamate dehydrogenase 1, mitochondrial			+	+
Q9WVE8	Protein kinase C and casein kinase substrate in neurons protein 2			+	+
P68373	Tubulin α-1C chain			+	+
P99024	Tubulin β-5 chain			+	+
Q60597	2-oxoglutarate dehydrogenase, mitochondrial		+
Q9D8E6	60 S ribosomal protein L4		+
P62897	Cytochrome c, somatic		+
Q99LB2	Dehydrogenase/reductase SDR family member 4		+
P58252	Elongation factor 2		+
Q64525	Histone H2B type 2-B		+
Q9ERE2	Keratin, type II cuticular Hb1 (Fragment)		+
Q78PY7	Staphylococcal nuclease domain-containing protein 1		+
Q9ERD7	Tubulin β-3 chain		+
P62270	40 S ribosomal protein S18			+
Q6ZWV3	60 S ribosomal protein L10			+
P60710	Actin, cytoplasmic 1			+
P48962	ADP/ATP translocase 1			+
Q03265	ATP synthase subunit α, mitochondrial			+
P56480	ATP synthase subunit β, mitochondrial			+
Q8BFZ3	β-actin-like protein 2			+
P16858	Glyceraldehyde-3-phosphate dehydrogenase			+
P30681	High mobility group protein B2			+
Q9D646	Keratin, type I cuticular Ha4			+
Q6IMF0	Keratin, type II cuticular Hb3			+
Q8R429	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1			+
P05214	Tubulin α-3 chain			+
P68372	Tubulin β-2C chain			+
P28653	Biglycan				+
Q9CZU6	Citrate synthase, mitochondrial				+
Q9QZQ8	Core histone macro-H2A.1				+
Q99020	Heterogeneous nuclear ribonucleoprotein A/B				+
Q9Z130	Heterogeneous nuclear ribonucleoprotein D-like				+
Q9Z2X1	Heterogeneous nuclear ribonucleoprotein F				+
Q8VEK3	Heterogeneous nuclear ribonucleoprotein U				+
P63158	High mobility group protein B1				+
Q8R1M2	Histone H2A.J				+
Q9D2U9	Histone H2B type 3-A				+
P84244	Histone H3.3				+
P62960	Nuclease-sensitive element-binding protein 1				+
P09405	Nucleolin				+
Q8BK67	Protein RCC2				+
P27005	Protein S100-A8				+
P54276	REVERSED DNA mismatch repair protein Msh6				+
Q921I1	Serotransferrin				+
P26039	Talin-1				+
Q9D0R2	Threonyl-tRNA synthetase, cytoplasmic				+
Q9CWF2	Tubulin beta-2B chain				+
Q91X17	Uromodulin				+
P50544	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial				+

Kidney extract on each indicated day after UUO surgery was incubated with biotinylated pepT26. The newly identified possible substrates in each indicated day were demonstrated as “+” compared to control sample (Day 0). The underlined possible substrates indicate overlapped substrates identified as both peptide (pepK5 and pepT26)-incorporated proteins.